http://alii-diet-pills.blog.co.uk/Alli diet pill, manufactured by GlaxoSmithKline, is the first over-the-counter weight loss diet pill approved by the Food and Drug Administration (FDA), graces the shelves of a drug and provides more benefit associated with weight loss.en-EUMokoFeed10http://alii-diet-pills.blog.co.uk/http://data5.blog.de/design/preview/8e/8d155ae8575f235408b12989d484d4_160x200.jpghttp://alii-diet-pills.blog.co.uk/2007/07/23/560kg_weight_mexican_man_into_record_boo~2685869/tag:alii-diet-pills.blog.co.uk,2007-07-23:/2007/07/23/560kg_weight_mexican_man_into_record_boo~2685869/Mon, 23 Jul 2007 12:25:02 +0200 <p><img src="http://d.yimg.com/us.yimg.com/p/afp/20070720/capt.sge.dwc24.200707210407.photo00.photo.default-512x342.jpg?x=380&y=253&sig=ceUl4XJTBNU0obSugkMZKw--" alt="Overweight" title="weight loss" width="320" height="160"></p> Mexico (AFP) - A Mexican tipping the scales at 560 kilograms (1,234 pounds) will be listed as the world's fattest man by the Guinness Book of Records, while a loss of 200 kilos (440 pounds) may make him the man who lost the most weight. </p> <p>"I am glad to be in the Guinness Book as the fattest man. I am also happy to have lost 200 kilos," Manuel Uribe, 41, told AFP.<br> Uribe was able to leave his home in Monterrey, northern Mexico in March aboard a trailer to celebrate his weight loss.</p> <p>Guinness has recognized his weighty achievement with a glass plaque.<br> "They gave it to me, I have it in my hands," said Uribe, who founded an organization to help overweight people.</p> <p>Uribe's photograph appears in the 2008 Guinness Book of Records alongside a description of the treatment he has had and offers of surgery he has received.</p> <p>Uribe said the editor of the book had promised to visit him next year, and held out the possibility of appearing in the 2009 edition as the man who had lost the most weight.</p> <p>Uribe appeared on television in 2006 seeking help for his excess weight, which has plagued him for more than 20 years, most of which he has spent in bed.</p> <p>source:http://news.yahoo.com/s/afp/20070720/od_afp/mexicohealthobesity_070720210958 <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/07/23/560kg_weight_mexican_man_into_record_boo~2685869/#comments">Comments</a> </small> </p>excess-weightover-weightweight-losshttp://alii-diet-pills.blog.co.uk/2007/07/23/560kg_weight_mexican_man_into_record_boo~2685869/#commentshttp://alii-diet-pills.blog.co.uk/2007/07/09/obesity_diet_drug_weapon_for_cancer~2600533/tag:alii-diet-pills.blog.co.uk,2007-07-09:/2007/07/09/obesity_diet_drug_weapon_for_cancer~2600533/Mon, 09 Jul 2007 10:28:31 +0200 The diet drug used to treat obesity has some benefits for cancer victim. </p> <p>Five years ago, scientists at Wake Forest University School of Medicine were surprised to find the drug orlistat (Xenical or Alli) could kill cancer cells. Now, they report on how it works. The drug binds and interacts with a protein found in tumor cells, blocking its function and causing the cells to die.</p> <p>The protein is known as fatty acid synthase. It is found in many tumor cells including those of the prostate, breast, colon, ovaries, liver, lung, and brain.</p> <p>“High levels of fatty acid synthase correlate with a poor prognosis, so it is a great treatment target," assistant professor Steven Kridel, Ph.D., of Wake Forest University School of Medicine, was quoted as saying. "This makes an exciting treatment target because, theoretically, you don't have to worry about harming nearby healthy tissue."</p> <p>Researchers say <a href="http://alii-diet-pills.blog.co.uk">Alli</a> or Xenical (orlistat) alone cannot treat cancer because while the drug can kill cancer cells in the lab, it is designed to act only in the digestive tract in humans. Now, the goal is to develop a drug like orlistat that can go through the bloodstream to the site of the tumor.</p> <p>Wake Forest scientists have screened hundreds of thousands of compounds to find the ones that interact with cancer cells like orlistat does. They have narrowed down the list to a dozen and will now work to optimize the compounds to determine if they can create a potent cancer treatment.</p> <p>Fatty acid synthase is also found in fat cells. This suggests if scientists successfully develop a drug to treat cancer, it could also be used to treat obesity. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/07/09/obesity_diet_drug_weapon_for_cancer~2600533/#comments">Comments</a> </small> </p>obesityalliorlistatexenicalhttp://alii-diet-pills.blog.co.uk/2007/07/09/obesity_diet_drug_weapon_for_cancer~2600533/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/27/over_the_counter_alli_diet_pill_showing_~2527443/tag:alii-diet-pills.blog.co.uk,2007-06-27:/2007/06/27/over_the_counter_alli_diet_pill_showing_~2527443/Wed, 27 Jun 2007 07:03:23 +0200 <p> <img src="http://www.myspaceantics.com/images/funny/fatty-bike.jpg" alt="Reduce weight with alli" title="over the counter pill, alli " width="260" height="160"></p> The first <a href="http://www.slimroute.com/alli_diet_pills.html">nonprescription diet drug Alli</a> is flying off store shelves, but most people who use it will lose very little weight and may experience embarrassing side effects.</p> <p>Most people who shed pounds using <strong>weight-loss alli diet pill </strong>will not be able to keep the weight off. Unlike other prescription weight-loss diet drugs such as Phentermine, adipex and meridia, Alli diet pill doesn't make you feel full, reduce cravings or curb your appetite. Instead, it prevents the body from breaking down and absorbing fat.</p> <p>The active ingredient in Alli diet pill is orlistat, which is found in a higher dose in the prescription diet drug Xenical. Alli diet pill blocks about 25 percent of the fat you eat; Xenical blocks one-third of the fat you ingest. For instance, a half-cup serving of Haagen-Dazs ice cream has about 320 calories and 19 grams of fat. </p> <p><a href="http://alii-diet-pills.blog.co.uk">Alli diet pill</a>, which is taken with meals, would prevent the body from absorbing about 4.75 fat grams or about 43 calories. If you consume about 2,000 calories a day and eat about 30 percent fat, the fat-blocking benefits of Alli diet pill would translate to about 150 calories a day. A pound of weight loss equals 3,500 calories.</p> <p> To avoid the side effects, limiting fat intake to 15 grams a meal. Many Americans consume 80 to 100 grams of fat every day. Glaxo officials concede that many people would lose weight on their own with a diet that's moderate in fat, but that the pill helps them lose more weight. If you would lose 10 pounds on a diet, you'll lose 15 pounds by adding Alli diet pill to your diet. </p> <p>If someone is consuming a diet already low in fat and high in carbohydrates, they likely would not get much benefit from Alli diet pill. However, doctors say most people are eating far more fat than they realize.</p> <p> Orlistat has been used by an estimated 28 million people worldwide and studied in 30,000 subjects in about 100 trials. In a 1999 Journal of the American Medical Association report, 1,187 dieters, who weighed an average of 220 pounds, took either a placebo or 120 mg of orlistat (twice the dose of Alli diet pill). After one year, individuals in the orlistat group lost an average of 19.27 pounds, about 50 percent more than the 12.8-pound average weight loss in the placebo group.</p> <p> But as with most diets, the dieters couldn't keep the weight off. During the second year of the study, the orlistat users were given either the 120 mg dose or switched to 60 mg, the same dose in Alli diet pill. After a year, the 120 mg users gained back seven pounds, the 60 mg users gained 9.4 pounds and the placebo group gained 11.3 pounds. So after two years on the drug, the dieters lost an average of between 10 and 12 pounds — or about 5 percent of their body weight. The placebo dieters lost 1.5 pounds.</p> <p>Some dieters lost far more weight. About 50 percent of the people who use orlistat. lose at least 5 percent of their body weight. One out of five people who take the drug lose at least 10 percent of their body weight. <p>source:http://deseretnews.com/dn/view/0,1249,680193224,00.html</p> <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/27/over_the_counter_alli_diet_pill_showing_~2527443/#comments">Comments</a> </small> </p>allialli-side-effectnon-prescription-drughttp://alii-diet-pills.blog.co.uk/2007/06/27/over_the_counter_alli_diet_pill_showing_~2527443/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/20/alli_diet_drug_work_better_with_healthy_~2485820/tag:alii-diet-pills.blog.co.uk,2007-06-20:/2007/06/20/alli_diet_drug_work_better_with_healthy_~2485820/Wed, 20 Jun 2007 10:41:04 +0200 <p>First over-the-counter medicine diet pill Alli works with, exercise and good food with low calorie diet. The first and only over-the-counter product for weight loss approved by the Food and Drug Administration is available in US now.<br> Alli (Orlistat) works by decreasing the amount of fat absorbed by the body. It is the Over the counter low version of Xenical. The good news: Alli (Orlistat) has been tested and the prescription version has been used since 1999.</p> <p>Previously, the drug's effects had only been studied in obese individuals. Study participants took either orlistat or a placebo three times daily with meals for 16 weeks. Results show those taking Over-the-counter strength <a href="http://alii-diet-pills.blog.co.uk">alli diet pill </a>(orlistat) did lose more weight than those doing only dieting</p> <p>Our research showed that people taking orlistat and following low-fat diets lost almost five percent of their initial body weight, about seven to 15 pounds, over four months.</p> <p> While two to four pounds a month isn't dramatic, steady weight loss of this amount can have major health benefits. For example, the reduction in LDL-cholesterol, the bad-guy cholesterol, of 10 percent can reduce risk of heart attack by 20 percent.</p> <p>Any successful dieter knows that long-term weight loss is about lifestyle changes not quick fixes. While taking Alli may help you lose weight, it won't do all of the work for you.</p> <p> Anderson stresses a healthy diet and exercise plan are absolutely necessary to lose the<br> Anderson said. "If people are commit to exercise six days a week, most people can lose weight steadily. All of us are in this for the long haul and need to keep up healthy behaviors, not for days or weeks, but for months and years.</p> <p> Doing regular physical activity and making proper diet choices will help us be trimmer and give us more energy.</p> <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/20/alli_diet_drug_work_better_with_healthy_~2485820/#comments">Comments</a> </small> </p>diet-pillalliorlistatlose-weighthttp://alii-diet-pills.blog.co.uk/2007/06/20/alli_diet_drug_work_better_with_healthy_~2485820/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/19/weighing_the_pros_and_cons_of_new_fat_bl~2478363/tag:alii-diet-pills.blog.co.uk,2007-06-19:/2007/06/19/weighing_the_pros_and_cons_of_new_fat_bl~2478363/Tue, 19 Jun 2007 05:46:05 +0200 <p><a href="http://www.blog.co.uk/srv/media/media_item.php?item_ID=1705643" title="Alli diet pill"><img src="http://data4.blog.de/media/643/1705643_cedb366d29_m.jpg" alt="Alli diet pill" vspace="5" hspace="5"></a><br> The new nonprescription <a href="http://www.slimroute.com/alli_diet_pills.html"><strong>diet drug Alli</strong></a> is flying off store shelves, but most people who use it will lose very little weight and may experience embarrassing side effects.</p> <p>Pharmacies are reporting brisk sales of Alli, which is sold by drug maker GlaxoSmithKline and is the first over-the-counter diet drug to win FDA approval. Unlike other prescription weight-loss drugs such as Meridia and the generic phentermine, Alli doesn't make you feel full, reduce cravings or curb your appetite. Instead, it prevents the body from breaking down and absorbing fat.</p> <p>The active ingredient in Alli is orlistat, which is found in a higher dose in the prescription diet drug Xenical. Alli blocks about 25% of the fat you eat; Xenical blocks one-third of the fat you ingest. Alli, which is taken with meals, would prevent the body from absorbing about 4.75 fat grams or about 43 calories. </p> <p>The downside of Alli is the fat it blocks can come out of your body in embarrassing ways. Glaxo said that drug can cause gas with oily discharge as well as frequent or loose stools. The site suggests it's probably a "smart idea" to wear dark pants and bring a change of clothes to work if you use Alli.</p> <p>To avoid the side effects, Glaxo suggests limiting fat intake. Glaxo officials concede that many people would lose weight on their own with a diet that's moderate in fat, but that the pill helps them lose more weight.</p> <p>If you'd lose 10 pounds on a diet, you'll lose 15 pounds by adding Alli to your diet.</p> <p>If someone is consuming a diet already low in fat and high in carbohydrates, they likely won't get much benefit from Alli. However, doctors say most people are eating far more fat than they realize.</p> <p><strong>Orlistat</strong> has been used by an estimated 28 million people world-wide, and studied in 30,000 subjects in about 100 trials. But as with most diets, the dieters couldn't keep the weight off. During the second year of the study, the Orlistat users were given either the 120 mg dose or switched to 60 mg, the same dose in Alli. </p> <p>Some dieters lost far more weight. About 50% of the people who use Orlistat lose at least 5% of their body weight. One out of five people who take the drug lose at least 10% of their body weight, according to Glaxo. </p> <p>Even small amounts of weight loss offer clear-cut health benefits. It's not for the average person who wants to take it and doesn't want to change their diet. It's for someone who is committed to making a change in diet and lifestyle. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/19/weighing_the_pros_and_cons_of_new_fat_bl~2478363/#comments">Comments</a> </small> </p>anti-obesity-drugsalli-diet-pillsover-the-counter-diet-pillsxenicalalli-diet-pillalli-diet-drugappetite-suppressantobesityhttp://alii-diet-pills.blog.co.uk/2007/06/19/weighing_the_pros_and_cons_of_new_fat_bl~2478363/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/18/doctors_weigh_in_on_new_diet_drug_alli~2472445/tag:alii-diet-pills.blog.co.uk,2007-06-18:/2007/06/18/doctors_weigh_in_on_new_diet_drug_alli~2472445/Mon, 18 Jun 2007 07:49:42 +0200 <p><a href="http://www.blog.co.uk/srv/media/media_item.php?item_ID=1701995" title="Alli diet pill"><img src="http://data4.blog.de/media/995/1701995_575218351b_m.jpg" alt="Alli diet pill" vspace="5" hspace="5"></a><br> The first FDA-approved <strong>over-the-counter-weight loss pill</strong> is on the market. The pill is supposed to help people lose 50 percent more weight than other diet supplements, but the new pill has some side effects that can keep you sidelined.</p> <p>Now you know there's no magic pill to lose weight, but doctors say Alli has some promise because it prevents the body from absorbing fat. </p> <p>The new pill is called Alli. It’s taken three times a day with a low-calorie diet. Doctors say you'll lose weight, but if you eat food in high in fat, you'll feel it.</p> <p>You don't want to go too far in depth because they're pretty nasty.</p> <p><a href="http://alii-diet-pills.blog.co.uk/"><strong>Alli</strong></a> works by preventing fats from being absorbed in your body. The bacteria see the fat coming and they have a party in your gut on the left over food and you’re in for some trouble.</p> <p>On Alli's website it lists gas with oily spotting and loose stool as part of the treatment effects. </p> <p>People want a magic way to weight loss, they don't want there intake to be the problem they don't want foods to be the problem and they don't want to their couch potato habits to be the problem they just want a miracle.</p> <p>These treatment effects however have not kept people from cleaning off the shelves at the Dunes Family Pharmacy. The pharmacy has sold out, and is waiting on another shipment.</p> <p>“It looks like its a drug that’s going to be sold out its going to be hard to get hopefully the supplier will be able to keep up with the demand so we can be able to keep it on stock,” says Benzoni.</p> <p>Diet and exercise are key to losing weight, with or without Alli or other weight loss programs. </p> <p>Alli is sold at all major drug and grocery stores in the area, but buying these diet pills on won't come cheap. 60 pills will set you back about 70 bucks. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/18/doctors_weigh_in_on_new_diet_drug_alli~2472445/#comments">Comments</a> </small> </p>xenicalalli-diet-drugappetite-suppressantanti-obesity-drugsobesityover-the-counter-diet-pillsalli-diet-pillsalli-diet-pillhttp://alii-diet-pills.blog.co.uk/2007/06/18/doctors_weigh_in_on_new_diet_drug_alli~2472445/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/15/alli_weight_loss_pill_hits_shelves_on_fr~2455481/tag:alii-diet-pills.blog.co.uk,2007-06-15:/2007/06/15/alli_weight_loss_pill_hits_shelves_on_fr~2455481/Fri, 15 Jun 2007 05:28:38 +0200 <p><a href="http://www.blog.co.uk/srv/media/media_item.php?item_ID=1692009" title="Alli diet pill"><img src="http://data4.blog.de/media/009/1692009_4b85aaf9c5_m.jpg" alt="Alli diet pill" vspace="5" hspace="5"></a><br> Glaxo Smith Kline's Alli, the first FDA-approved <strong>over-the-counter weight loss pill</strong>, hits shelves nationwide this Friday. Whether or not it succeeds depends on a large part on its multilingual, multi-million dollar marketing campaign. </p> <p>A fat absorption pill, <a href="http://alii-diet-pills.blog.co.uk/2007/06/08/dieters_may_have_new_alli_in_fighting_fl~2414484"><strong>Alli</strong></a> has labeled itself as an over the counter non-prescription "drug," but its marketing places heavy emphasis on its role as a supplement to a healthy lifestyle – the sort of remedy marketing, the researchers argue, that promote the pill's chances of working by encouraging complementary healthy behaviors such as exercise. </p> <p>First, drug marketing undermines motivation to live a healthy lifestyle – why bother eating low-fat foods when a drug exists to fight fat for me. Drugs also appear to weaken consumers' beliefs in their ability to live a healthy lifestyle by eating right and exercising. </p> <p>Interestingly, in a series of experiments and test groups, the researchers found that supplements did not have this same 'boomerang effect" on a healthy lifestyle: regardless of how effective the supplement actually is, consumer perceptions of supplements are that they require "supplementary" behavior in order to work. </p> <p>People appear to choose supplements almost as a matter of faith rather than science. They perceive these products as 'natural' and figure they can't hurt. And our research suggests that they don't - at least in terms of healthy lifestyle intentions.</p> <p>These findings add to the growing debate over the regulation of drug and supplement markets and the role of direct-to-consumer advertising. Alli marketing campaign – which emphasizes the pill's role in a healthy lifestyle that also includes menu planning and exercise – may soon lead other pharmaceutical companies to follow suit and play down the effectiveness of their products. </p> <p>More truthful approach to the marketing of these kinds of products may not be what consumers want to hear, but is promising because it is so different than the typical approach used to market these kinds of products. Usually, they are positioned as effective as some kind of easy, magic solution. This product is up front in educating consumers that the road to long term weight loss goals requires hard work and a long term commitment. Its effectiveness is maximized in conjunction with other behaviors.</p> <p>Alli has the right balance, but the present research suggests that Glaxo Smith Kline is moving in the right direction to protect consumer welfare. "Even highly educated consumers and consumers who have otherwise acknowledged the importance of a healthy lifestyle is nonetheless susceptible to the boomerang effect for drugs. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/15/alli_weight_loss_pill_hits_shelves_on_fr~2455481/#comments">Comments</a> </small> </p>anti-obesity-drugsalli-diet-pillobesityover-the-counter-diet-pillalli-diet-drugappetite-suppressantxenicalhttp://alii-diet-pills.blog.co.uk/2007/06/15/alli_weight_loss_pill_hits_shelves_on_fr~2455481/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/14/fda_panel_rejects_sanofi_aventis_acompli~2449267/tag:alii-diet-pills.blog.co.uk,2007-06-14:/2007/06/14/fda_panel_rejects_sanofi_aventis_acompli~2449267/Thu, 14 Jun 2007 04:51:44 +0200 <p><a href="http://www.blog.co.uk/srv/media/media_item.php?item_ID=1688656" title="acomplia sanofi"><img src="http://data4.blog.de/media/656/1688656_1feb460c6d_m.jpg" alt="acomplia sanofi" vspace="5" hspace="5"></a><br> A U.S. Food and Drug Administration panel unanimously rejected Acomplia, a weight-loss drug from French drug maker Sanofi-Aventis SA, based on safety concerns. </p> <p>An FDA spokeswoman said that the deliberations of the panel boiled down to, “Is the risk worth the benefit of this drug, and the panel said no." </p> <p>The FDA is due to make a decision on the approval for sale in the U.S. of Acomplia, known generically as Rimonabant, in late July.<br> Historically, the FDA follows the advice of the advisory committee when making approval decisions.</p> <p>FDA proposed that the vote against Acomplia was 14-0. </p> <p>Paris-based Sanofi-Aventis (SNY) issued a statement that it “will continue to work closely with the FDA to address the committee's recommendations." </p> <p>In a report prepared by the panel and published, concerns were raised about the safety of Acomplia, particularly its effect on users' mental health. Sanofi-Aventis submitted data and analyses on Acomplia for the panel's review late last year. </p> <p>"Adverse events" encountered during the testing of the drug included” depressive events, anxiety, psychomotor agitation, and sleep disorders," according to the panel's report. </p> <p>The FDA's Division of Metabolism and Endocrine Products has received a number of "event" reports from Sanofi-Aventis related to Acomplia, the report said, including "4 reports of delusional symptoms, 6 reports of psychotic behavior, and 5 reports of aggression". </p> <p>Rimonabant, the generic form of Acomplia, is approved in 37 countries and marketed in 18, according to Sanofi-Aventis. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/14/fda_panel_rejects_sanofi_aventis_acompli~2449267/#comments">Comments</a> </small> </p>appetite-suppressantacompliaweight-loss-tipsobesityacomplia-onlineacomplia-diet-pillseffective-diet-pillshttp://alii-diet-pills.blog.co.uk/2007/06/14/fda_panel_rejects_sanofi_aventis_acompli~2449267/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/13/fda_concerned_about_sanofi_obesity_drug_~2443134/tag:alii-diet-pills.blog.co.uk,2007-06-13:/2007/06/13/fda_concerned_about_sanofi_obesity_drug_~2443134/Wed, 13 Jun 2007 04:52:18 +0200 The U.S. Food and Drug Administration said that patients who took Acomplia, also known as Zimulti, in clinical trials were more likely to suffer from suicidal thoughts or actions than those on gesture.</p> <p>The notes were posted by US health experts, as is customary; decide whether to recommend the drug to the FDA health regulator for marketing approval.</p> <p><strong><a href="http://alii-diet-pills.blog.co.uk/2007/06/07/how_does_acomplia_rimonabant_work~2408582">Acomplia</a></strong> or rimonabant is an anorectic anti-obesity drug. It is a CB1 cannabinoid receptor antagonist. Its main avenue of effect is reduction in appetite. Rimonabant is currently being sold in the United Kingdom by Sanofi-Aventis and in Denmark by Sanofi-Synthelabo under the trade name Acomplia. It is believed, although not confirmed, that if the drug is approved in the United States, it will be sold under the trade name Zimulti.</p> <p>It is being reported that the FDA is concerned over Acomplia due to it appearing to raise a person's risk of attempting to commit suicide. The drug does actually work according to the FDA who stated that over a 1 year period, when combined with a good diet a person could lose up to 5% more than they would if they just dieted.</p> <p>The US FDA is set to ask an advisory panel to measure the benefits against the risks and decide if the drug should be marketed in the United States.</p> <p>Sanofi-Aventis reacted warily to a U.S. health review of anti-obesity pill Acomplia, highlighting its side-effects such as suicidal thoughts. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/13/fda_concerned_about_sanofi_obesity_drug_~2443134/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/06/13/fda_concerned_about_sanofi_obesity_drug_~2443134/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/12/glaxo_prepares_weight_loss_pill_alli_for~2436813/tag:alii-diet-pills.blog.co.uk,2007-06-12:/2007/06/12/glaxo_prepares_weight_loss_pill_alli_for~2436813/Tue, 12 Jun 2007 04:52:43 +0200 <p><a href="http://www.blog.co.uk/srv/media/media_item.php?item_ID=1681642" title="orlistat"><img src="http://data4.blog.de/media/642/1681642_767699f5f1_m.jpg" alt="orlistat" vspace="5" hspace="5"></a><br> GlaxoSmithKline Plc, the world's second-largest drugmaker after Pfizer Inc., will begin selling its weight-loss medicine alli directly to consumers in U.S. pharmacies this week. </p> <p>U.S. Food and Drug Administration approved over-the-counter version of the company's orlistat prescription diet medicine. It will be one of the largest launches GSK has ever undertaken, probably one of the largest over-the-counter launches ever.</p> <p>London-based Glaxo is selling the medicine without a prescription to help offset slowing revenue from its top-selling asthma drug Advair. An estimated 140 million adults in the U.S. were overweight or obese in 2004. The figures are based on body-mass index, which is calculated using a person's height and weight. </p> <p>Glaxo is also preparing 250 pages of educational materials to accompany the starter pack, a Web site, 200,000 copies of a diet plan and 800,000 copies of a book to help dieters combine the pill with weight-loss programs. People who take alli while improving their diets and exercise regimens can lose 50 percent more weight.</p> <p>The company is aiming the product at committed dieters who will help sustain sales rather than fad dieters who will buy alli and then drop it.</p> <p><strong>Orlistst</strong> costs about $270 for a one-month supply of 120- milligram pills and has been on the market for eight years. It brought in $90 million in the U.S. last year. The drug acts by blocking fat absorption in the stomach and intestines and doesn't affect the heart or brain.</p> <p>Glaxo markets the prescription version, known as Xenical, in the U.S. through an agreement.</p> <p>Glaxo plans to seek permission by the end of this year to sell the product without a prescription in Europe. About 40 percent of Europeans are overweight and 15 percent are obese. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/12/glaxo_prepares_weight_loss_pill_alli_for~2436813/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/06/12/glaxo_prepares_weight_loss_pill_alli_for~2436813/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/11/big_week_ahead_as_alli_goes_on_sale_what~2431535/tag:alii-diet-pills.blog.co.uk,2007-06-11:/2007/06/11/big_week_ahead_as_alli_goes_on_sale_what~2431535/Mon, 11 Jun 2007 10:24:32 +0200 A big week lies ahead for would-be dieters with over-the-counter <strong>diet pill alli</strong> (low-dose Xenical) set to go on sale on Friday June 15th and long-awaited prescription diet drug Acomplia facing its moment of truth at the FDA.</p> <p>The biggest question still hanging over alli, the only diet pill ever approved by the FDA for nonprescription sale, is whether supplies in pharmacies, supermarkets and retailers like Target and Wal-Mart will be sufficient to meet initial demand.</p> <p>But a lot of big questions continue to afflict the Sanofi-Aventis prescription drug rimonabant, which has been on sale as Acomplia in Europe for more than a year even though it remains stalled under a cloud of mystery at the FDA.</p> <p>Some hints as to rimonabant's immediate future in the United States should be a lot clearer by the end of this week. </p> <p>The following day, June 13th, the agency's Endocrinologic and Metabolic Drug Advisory Committee, a panel of outside experts, will air various concerns about Acomplia and its side-effects, and vote on whether to recommend FDA approval. </p> <p>While the FDA does not have to follow the recommendations of its advisory committees, it generally does -- and the combination of the staff report and the advisory panel vote should strongly signal what to expect in July when the regulatory agency's decision on approval of rimonabant is now due.<br> In a best case scenario for the developer of rimonabant, Sanofi-Aventis, Zimulti -- as it will be known in the United States -- could be on the market by early fall.</p> <p>Sanofi during this time has provided very few hints of what was holding up action at the FDA. </p> <p>But it long has been apparent that the FDA's questions for the most part do not involve the effectiveness this novel obesity treatment, which works by blocking the CB1 receptor in the brain, but center on the neuropsychiatric side-effects reported during the Acomplia clinical trials.</p> <p>Not only were worrisome instances of anxiety, depression and nausea experienced by a number of participants in the trials, but concern also has been voiced over the high drop-out rate from the trials among participants getting the dose of Acomplia submitted for approval to the FDA.</p> <p>Sanofi-Aventis has consistently downplayed concern over rimonabant's side effects, and has said it will be pleased to have the opportunity to present its data on rimonabant.</p> <p>But with the FDA freshly focused on safety concerns as a result of the recent furor over whether regulators were slow in getting out safety data on a GlaxoSmithKline diabetes drug, Sanofi and its hopes for rimonabant may well be in for a rocky week. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/11/big_week_ahead_as_alli_goes_on_sale_what~2431535/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/06/11/big_week_ahead_as_alli_goes_on_sale_what~2431535/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/08/dieters_may_have_new_alli_in_fighting_fl~2414484/tag:alii-diet-pills.blog.co.uk,2007-06-08:/2007/06/08/dieters_may_have_new_alli_in_fighting_fl~2414484/Fri, 08 Jun 2007 04:55:31 +0200 <p><a href="http://www.blog.co.uk/srv/media/media_item.php?item_ID=1668464" title="alli diet pills"><img src="http://data4.blog.de/media/464/1668464_761ff200bc_m.jpg" alt="alli diet pills" vspace="5" hspace="5"></a><br> Just how good is a weight-loss pill if it takes a reduced-calorie, low-fat diet and exercise to make it work?</p> <p>Alli, the 60-milligram over-the-counter version of orlistat, the weight-loss drug sold by prescription since 1999 under the brand name Xenical (120 mg capsules). Alli blocks the absorption of fat so that you lose about 50 percent more weight with it than without it, all else being equal.</p> <p>Alli (pronounced AL-eye) became the first non-prescription diet pill approved by the U.S. Food and Drug Administration this year and should be on the shelves of grocery stores, pharmacies and mass-market outlets June 15, but if you are waiting for a magic bullet to lose weight for you, Alli isn't it.</p> <p>A low-fat diet with 15 grams of fat or less per meal is recommended with Alli. Weight loss is about taking time for self-care. It's about changing your attitude, your behavior and your lifestyle. You have to start from a position of self-worth. Losing weight is a positive thing you do for yourself, not a punitive thing to make up for overeating.</p> <p>How does Alli work?<br> Alli is a fat blocker. It works by decreasing the amount of dietary fat that is digested. Does Alli have side effects? Yes, Alli blocks the absorption of fat, and that fat is passed out of the body in stools, so it can cause some gastrointestinal side effects, including diarrhea and cramping, especially if you eat a large amount of fat at one meal. </p> <p>How much can I lose with Alli?<br> It depends on your diet and exercise, but with Alli, You will lose about 50 percent more than you would without it. That is, for every 10 pounds you would normally lose, Alli will help you lose five more. If you are on a diet to lose 10 pounds in one month without the medicine, you should lose 15 with it.</p> <p>What can I do to maximize the benefits of Alli?<br> Write down everything you eat, and calculate how many fat grams each meal contains. A low-fat meal should have 15 or fewer fat grams. Most of us vastly underestimate how much we eat. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/08/dieters_may_have_new_alli_in_fighting_fl~2414484/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/06/08/dieters_may_have_new_alli_in_fighting_fl~2414484/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/07/how_does_acomplia_rimonabant_work~2408582/tag:alii-diet-pills.blog.co.uk,2007-06-07:/2007/06/07/how_does_acomplia_rimonabant_work~2408582/Thu, 07 Jun 2007 04:52:36 +0200 <p><a href="http://www.blog.co.uk/srv/media/media_item.php?item_ID=1665253" title="sanofi"><img src="http://data4.blog.de/media/253/1665253_de34237073_m.jpg" alt="sanofi" vspace="5" hspace="5"></a><br> How does Acomplia Work? Acomplia works just like an appetite suppressant, it blocks the receptor CB-1 which is found on the cells surfaces throughout the body parts of humans including fat cells. Such receptors act as a thin charge for food and nicotine intake, and are over-active in the obese. By targeting such CB-1 receptors. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/07/how_does_acomplia_rimonabant_work~2408582/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/06/07/how_does_acomplia_rimonabant_work~2408582/#commentshttp://alii-diet-pills.blog.co.uk/2007/06/05/diet_drug_acomplia_launched_in_united_ar~2397208/tag:alii-diet-pills.blog.co.uk,2007-06-05:/2007/06/05/diet_drug_acomplia_launched_in_united_ar~2397208/Tue, 05 Jun 2007 09:47:13 +0200 <p><a href="http://www.blog.co.uk/srv/media/media_item.php?item_ID=1658021" title="acomplia"><img src="http://data4.blog.de/media/021/1658021_7971d5ddbc_m.jpg" alt="acomplia" vspace="5" hspace="5"></a><br> Sanofi-Aventis has announced that Diet drug rimonabant (Acomplia / Zimulti) is now available in the United Arab Emirates for treatment of abdominally obese patients with cardiometabolic risk factors.</p> <p>This is the first announced launch of <a href="http://www.slimroute.com/acomplia.html">Acomplia</a> in the Middle East. The drug has been available for almost a year in Europe, and also is on sale in Argentina, Brazil and Mexico. </p> <p>A recent survey found that 37 percent of the UAE population is now obese -- one of the highest obesity rates in the Middle East, according to Sanofi.</p> <p>Among people who are overweight or obese, it is those with excess fat around their abdomen who are at the greatest risk of developing an abnormal lipid profile, type 2 diabetes and ultimately heart disease.</p> <p>Rimonabant is an important advance in the treatment of cardio-metabolic risk factors which contribute to the global risk for diabetes and cardiovascular disease.</p> <p>The launch of Acomplia will also feature an evening symposium for UAE doctors on the risks of abdominal obesity. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/06/05/diet_drug_acomplia_launched_in_united_ar~2397208/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/06/05/diet_drug_acomplia_launched_in_united_ar~2397208/#commentshttp://alii-diet-pills.blog.co.uk/2007/05/31/weight_loss_drug_outsells_viagra~2365028/tag:alii-diet-pills.blog.co.uk,2007-05-31:/2007/05/31/weight_loss_drug_outsells_viagra~2365028/Thu, 31 May 2007 06:19:18 +0200 A weight-loss drug has become more popular than Viagra in Taiwan. More than 6 million tablets of the weight-loss drug were sold in Taiwan last year. Weight loss drugs are the 18th best-selling drug on the market, according to IMS Health Inc.</p> <p>In contrast, the sales ranking of Viagra fell from ninth place in 2005 to 19th last year. A total of 710,000 pills of Viagra were sold in 2006. Urologists say Viagra's drop in sales may be from the economic slowdown and the high cost of the pill at US$12(NT$400) each. The drop in Viagra sales could also be from competition from other sexual enhancer medications. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/05/31/weight_loss_drug_outsells_viagra~2365028/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/05/31/weight_loss_drug_outsells_viagra~2365028/#commentshttp://alii-diet-pills.blog.co.uk/2007/05/30/mega_t_green_tea_for_weight_loss~2358666/tag:alii-diet-pills.blog.co.uk,2007-05-30:/2007/05/30/mega_t_green_tea_for_weight_loss~2358666/Wed, 30 May 2007 05:07:42 +0200 Looking to lose weight without resorting to drugs? Look no more! Mega-T Green Tea is the stuff to go for!</p> <p>You can start shedding those extra twenty pounds in a flash by using newest Mega-T Green Tea. You will have a better experience with Mega-T Green Tea for Weight Loss.</p> <p>Mega-T Green Tea contains a high amount of Green Tea extract that helps curb your appetite. Green tea contains substances that act as a natural <a href="http://www.slimroute.com/apetite_suppressant.html">appetite-suppressant</a>. So with Mega-T Green Tea, you no longer have to worry about those afternoon hungry pangs. And with Mega-T Green Tea, getting up in the middle of the night to binge is a thing of the past! No binge, no bulge!</p> <p>Mega-T Green Tea also contains chromium. Chromium in Mega-T Green Tea is highly valued because it helps reduce fats by increasing your metabolic rates. Therefore, fat-burning happens quickly when you use Mega-T Green Tea!</p> <p>Mega-T Green Tea Diet is the newest weight loss product to hit the market. A unique blend of green tea and other ingredients, Mega-T Green Tea Diet is the one product that can promote mega weight loss.</p> <p>Mega-T Green Tea Diet helps increase your body's metabolic rates and helps you burn fats faster. More fats burned means more weight lost! <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/05/30/mega_t_green_tea_for_weight_loss~2358666/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/05/30/mega_t_green_tea_for_weight_loss~2358666/#commentshttp://alii-diet-pills.blog.co.uk/2007/05/29/diet_pills_not_magic_bullet~2352061/tag:alii-diet-pills.blog.co.uk,2007-05-29:/2007/05/29/diet_pills_not_magic_bullet~2352061/Tue, 29 May 2007 05:06:24 +0200 Is there any medication that can help to lose weight? This is a big question generally comes in mind of all obese people. Whenever you lose “just” 10 percent of your initial body weight there are amazing subsequent benefits to your health. However, maintaining these weight and health benefits can be the challenge. Be realistic when you set your weight-loss goals.</p> <p>If you've decided to lose weight the next question is how to lose it. When you type "diet" into Google, 144 million results come up. Obviously when there are so many choices, none of them are perfect. Pharmaceutical companies have been searching for that magic diet pill for as long as this problem has existed, because they realize its potential for health and wealth.</p> <p>There are currently only two weight-loss medications that have been approved for use for up to 12 months by the FDA. The first is sibutramine (brand name Meridia).</p> <p>The second drug approved by the FDA for weight loss is Orlistat (brand name Xenical). This medication helps prevent the absorption of fat in the stomach and the small intestine.</p> <p>There is also a medication that's been available in Great Britain since July 2006. Its generic name is rimonabant and its brand name is Acomplia.</p> <p>Yes, these are medications that can help with weight loss, but these are not magic bullet. If you want to use of weight loss drugs you should be carefully followed by your physician. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/05/29/diet_pills_not_magic_bullet~2352061/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/05/29/diet_pills_not_magic_bullet~2352061/#commentshttp://alii-diet-pills.blog.co.uk/2007/05/28/alli_diet_drug_not_a_miracle~2346307/tag:alii-diet-pills.blog.co.uk,2007-05-28:/2007/05/28/alli_diet_drug_not_a_miracle~2346307/Mon, 28 May 2007 07:50:35 +0200 GlaxoSmithKline opened an educational exhibit in New York City to prepare the country for "alli," the first over-the-counter diet pill approved by the Food and Drug Administration.</p> <p>While the cautionary marketing approach might not trigger stampedes to the counter, analysts say the drug's fate hinges on the pharmaceutical giant's ability to convince people that diet pills aren't a magic bullet.</p> <p>People's hopes are ridiculously high when it comes to diet pills. That leads to disappointment and bad word of mouth. People were let down when it failed to deliver dramatic results, and the drug never really caught on. GlaxoSmithKline has apparently learned the lesson and is counting on alli to become a star money-maker.</p> <p>In clinical trials, the FDA says that people using <a href="http://alii-diet-pills.blog.co.uk/">alli</a> lost an additional 2 to 3 pounds for every 5 pounds lost through diet and exercise. The FDA approved alli in February to be sold over the counter.</p> <p>About half of patients in trials experienced gastrointestinal side effects, including leakages and oily discharges. GlaxoSmithKline is frank about those unpleasant effects, which it says can be controlled with proper use. </p> <p>One of the things we've seen so often in advertisements is that a drug can be an alternative to a healthy lifestyle. Still, question arise that whether a diet drug had any role in a campaign about healthy lifestyles. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/05/28/alli_diet_drug_not_a_miracle~2346307/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/05/28/alli_diet_drug_not_a_miracle~2346307/#commentshttp://alii-diet-pills.blog.co.uk/2007/05/25/green_tea_diet_pills~2329973/tag:alii-diet-pills.blog.co.uk,2007-05-25:/2007/05/25/green_tea_diet_pills~2329973/Fri, 25 May 2007 05:54:57 +0200 People want to make themselves look nice. These days, television, magazines and newspapers are constantly feeding us with ideas on the perfect body. But truth be told, majority of us do not have the model figures to make it to the cut. It is not a shocker then when a multi-billion industry could spring from weight loss products like diet pills.</p> <p>Too many diet pills and products are available in the market today that it is hard to determine which one really works. Several manufacturing companies specializing in diet pills and other weight loss products are quick to claim the effectiveness of their diet pills even without proper scientific backing. Some diet pills even contain substances that have harmful effects to the body.</p> <p>Diet pills like ephedra have been to known to cause complications from cardiovascular palpitations to hypertension and diarrhea. Several cases have been reported by the FDA of the harmful effects of diet pills and other weight loss products. </p> <p>Though some diet pills contain harmful elements, not all diet pills are bad. Diet pills made from herbs can have several benefits aside from weight loss. Some of these herbal diet pills come from plants such as nettle, green tea, and dandelion.</p> <p>Green tea is an herb popularly used in making diet pills. Green tea is derived from the plant Carmellia sinensis, the same plant made in concocting black and oolong tea. The process of making green tea makes it different from the other Carmellia sinensis teas. Because green tea is only mildly steamed and then dried, a majority of the beneficial antioxidants present in green tea remain intact. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/05/25/green_tea_diet_pills~2329973/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/05/25/green_tea_diet_pills~2329973/#commentshttp://alii-diet-pills.blog.co.uk/2007/05/24/acomplia_diet_pills_achieve_optimistic_w~2324646/tag:alii-diet-pills.blog.co.uk,2007-05-24:/2007/05/24/acomplia_diet_pills_achieve_optimistic_w~2324646/Thu, 24 May 2007 09:40:36 +0200 <p><a href="http://www.blog.co.uk/srv/media/media_item.php?item_ID=1616215" title="weight loss"><img src="http://data4.blog.de/media/215/1616215_e5b29689e7_s.jpg" alt="weight loss" vspace="5" hspace="5"></a></p> Acomplia diet pills have along been in the news for its effectiveness in weight loss. It had already approved in Europe as a prescription weight loss drug and waiting for FDA approval in USA as an appetite suppressant. Better results given by Acomplia weight loss drug make it very popular in Europe and other countries.</p> <p>Basically acomplia is an oral prescription weight loss drug which works on the neuro-transmitters, which are responsible for amendable appetite in the body. Amongst obese or overweight individuals, these transmitters tend to be overactive to feel hunger. Consumption of Acomplia basically obstructs the over-activity of these neuro-transmitters, thereby reducing the normal appetite of an obese or an overweight individual.</p> <p>This effective weight loss medication, Acomplia is usually recommended for obese who have BMI 28 or overweight who have BMI27 with health risk factors. In order to get well-acquainted whether Acomplia is suitable for you or not, speak with your doctor. </p> <p>Your doctor can suggest a pertinent dosage in accordance to your medical condition and requirement. It is a prescription medication one should not alter the recommended dosage without medical consultation. This medication is suggested to be accompanied with a proper diet plan and regular workout regime in order to achieve optimistic weight loss results. </p> <p>Acomplia diet drug can be accessed easily by means of online pharmacies. It can make your purchase expedient and also responsible to save your time with minimum efforts. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/05/24/acomplia_diet_pills_achieve_optimistic_w~2324646/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/05/24/acomplia_diet_pills_achieve_optimistic_w~2324646/#commentshttp://alii-diet-pills.blog.co.uk/2007/05/23/alli_next_boom_in_healthcare_industry~2319441/tag:alii-diet-pills.blog.co.uk,2007-05-23:/2007/05/23/alli_next_boom_in_healthcare_industry~2319441/Wed, 23 May 2007 12:04:10 +0200 The landscape for weight loss is about to change. A diet pill that once needed a doctor’s prescription is soon to hit stores. But before you think this is a "magic" pill, there are some "interesting" side effects even the company wants you to know.</p> <p>It's called Alli and it's a lower dose version of the prescription weight loss pill Xenical. The active ingredient in both is Orlistat, which works by limiting the amount of fat your body absorbs from food.<br> Glaxo Smith Kline strongly disagrees, and said the FDA reviewed 10 years of safety data from around the world before giving the final approval to Alli diet pills. </p> <p><a href="http://www.slimroute.com/alli_diet_pills.html">Alli diet pills</a> really is not going to be a magic pill, but still new over-the-counter version, Alli, would be accessible to more people who want to jump start weight loss.</p> <p>Alli is not absorbed into the system, it doesn't affect your central nervous system, it doesn't affect your brain, it doesn't affect your cardiovascular system, and it doesn't mess with your heart. It acts in the gut, that's a pretty safe place. <p> <small> <a href="http://alii-diet-pills.blog.co.uk/2007/05/23/alli_next_boom_in_healthcare_industry~2319441/#comments">Comments</a> </small> </p>http://alii-diet-pills.blog.co.uk/2007/05/23/alli_next_boom_in_healthcare_industry~2319441/#comments